Gamma-glutamyltransferase levels, prediabetes and type 2 diabetes: a Mendelian randomization study
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چکیده
منابع مشابه
Alcohol Use and Gamma-Glutamyltransferase Using a Mendelian Randomization Design in the Guangzhou Biobank Cohort Study
BACKGROUND Observational studies and small intervention studies suggest alcohol raises gamma-glutamyltransferase (GGT). We used Mendelian randomization to assess the causal effect of alcohol use on GGT in older Chinese people. METHODS An instrumental variable (IV) analysis in 2,321 men and 2,757 women aged 50+ years from phase 3 of the Guangzhou Biobank Cohort Study with ALDH2 (rs671) genotyp...
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Many biomarkers are associated with type 2 diabetes (T2D) risk in epidemiological observations. The aim of this study was to identify and summarize current evidence for causal effects of biomarkers on T2D. A systematic literature search in PubMed and EMBASE (until April 2015) was done to identify Mendelian randomization studies that examined potential causal effects of biomarkers on T2D. To rep...
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ژورنال
عنوان ژورنال: International Journal of Epidemiology
سال: 2017
ISSN: 0300-5771,1464-3685
DOI: 10.1093/ije/dyx006